Quinidine Injection (Quinidine Gluconate Injection) Drug Overview and Uses for Patients and Caregivers at RxList

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May 27, 2012

Quinidine Injection

Palpitations »

Palpitations facts

Palpitations can occur without heart disease or as a result of abnormal heart rhythms (arrhythmias).
The SA node is the natural pacemaker of the heart.
Slow heart rhythms are called bradycardias. Rapid heart rhythms are called tachycardias.
The average normal heart beats at a rate of 60 to 100 times per minute.
Some patients with arrhythmias have no symptoms while others can have symptoms, such as palpitations, dizziness, shortness of breath, or chest pain.
Arrhythmias can occur because of disease of the heart muscle, valves, electrical system, or arteries to the heart (coronary arteries).
Palpitations can be evaluated with testing, such as blood tests, echocardiogram, EKG, Holter monitor, treadmill testing, and tests of the coronary arteries.
Palpitations can be relieved in many patients by stress reduction, quitting smoking, and reduction of caffeine and alcohol.

Read the Palpitations article »

Quinidine Injection

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QUINIDINE GLUCONATE
(quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) ) Injection

DRUG DESCRIPTION

Quinidine is an antimalarial schizonticide and an antiarrhythmic agent with class 1a activity; it is the d–isomer of quinine and its molecular weight is 324.43. Quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) is the gluconate salt of quinidine; its chemical name is cinchonan–9–ol, 6'– methoxy–, (9S)–, mono–D–gluconate; its structural formula is

Quinidine Gluconate Structural Formula Illustration

its empirical formula is C₂₀H₂₄N₂O₂•C₆H₁₂O₇, and its molecular weight is 520.58, of which 62.3% is quinidine base.

Each vial of Quinidine Gluconate Injection contains 800 mg (1.5 mmol) of quinidine gluconate (quinidine gluconate (quinidine gluconate injection) injection) (500 mg of quinidine) in 10 mL of Sterile Water for Injection, 0.005% of edetate disodium, 0.25% phenol, and (as needed) D–gluconic acid d–lactone to adjust the pH.

Last reviewed on RxList: 5/21/2009
This monograph has been modified to include the generic and brand name in many instances.