"The U.S. Food and Drug Administration today approved Kcentra (Prothrombin Complex Concentrate, Human) for the urgent reversal of vitamin K antagonist (VKA) anticoagulation in adults with acute major bleeding. Plasma is the only other product appr"...
- Clinician Information:
Quinidine Sulfate Consumer (continued)
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: arbutamine, cisapride, fingolimod, propafenone.
Other medications can affect the removal of quinidine from your body, which may affect how quinidine works. Examples include mifepristone, certain azole antifungals (including fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole), certain protease inhibitors (such as nelfinavir, ritonavir, tipranavir), among others.
This medication can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include aliskiren, digoxin, mefloquine, tricyclic antidepressants (such as desipramine, imipramine), among others.
Many drugs besides quinidine may affect the heart rhythm (QT prolongation), including artemether/lumefantrine, ranolazine, toremifene, antiarrhythmic drugs (such as amiodarone, disopyramide, dofetilide, dronedarone, ibutilide, procainamide, sotalol), antipsychotics (such as pimozide, thioridazine, ziprasidone), certain quinolone antibiotics (grepafloxacin, sparfloxacin), among others.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: large amounts of antacids (e.g., sodium bicarbonate), barbiturates (e.g., phenobarbital), carbamazepine, rifamycins (e.g., rifampin, rifabutin), phenytoin, carbonic anhydrase inhibitors (e.g., acetazolamide), aripiprazole, atomoxetine, codeine, hydrocodone, loperamide, medication for high blood pressure (e.g., nifedipine, verapamil, diltiazem), certain macrolide antibiotics (e.g., erythromycin, clarithromycin), quinupristin/dalfopristin, etravirine, fosamprenavir.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness/fainting, hallucinations, seizures.
NOTES: Do not share this medication with others.
Laboratory and/or medical tests (e.g., complete blood count, liver/kidney function tests, quinidine blood levels, EKG) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada).
Information last revised August 2013. Copyright(c) 2013 First Databank, Inc.
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