The most frequently reported adverse events in the overall study population were transient decreased vision, fever, foreign body sensation, headache, transient ocular burning, ocular pain or discomfort, pharyngitis and photophobia. These events occurred in approximately 1-3% of patients. Other reported reactions occurring in less than 1% of patients included allergic reactions, lid edema, ocular dryness, and ocular itching.

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Specific drug interaction studies have not been conducted with QUIXIN® (levofloxacin ophthalmic solution 0.5%) . However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives, and has been associated with transientelevations in serum creatinine in patients receiving systemic cyclosporine concomitantly.

Last reviewed on RxList: 12/18/2008
This monograph has been modified to include the generic and brand name in many instances.