"The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to treat adults and some adolescents with giant cell tumor of the bone (GCTB), a rare and usually non-cancerous tumor.
GCTB generally occurs in a"...
(Generic versions may still be available.)
- Clinician Information:
Raxar Patient Information including If I Miss a Dose
In this Article
- What is grepafloxacin (Raxar)?
- What are the possible side effects of grepafloxacin (Raxar)?
- What is the most important information I should know about grepafloxacin (Raxar)?
- Who should not take grepafloxacin (Raxar)?
- How should I take grepafloxacin (Raxar)?
- What happens if I miss a dose (Raxar)?
- What happens if I overdose (Raxar)?
- What should I avoid while taking grepafloxacin (Raxar)?
- What other drugs will affect grepafloxacin (Raxar)?
- Where can I get more information?
What happens if I miss a dose (Raxar)?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
What happens if I overdose (Raxar)?
Seek emergency medical attention.
The most common symptom of a grepafloxacin overdose is irregular or slow heartbeats.
What should I avoid while taking grepafloxacin (Raxar)?
Avoid prolonged exposure to sunlight. Grepafloxacin increases the sensitivity of the skin to sunlight, and a severe sunburn may result. If sun exposure is unavoidable, wear protective clothing and use sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun.
Use caution when driving, operating machinery, or performing other hazardous activities. Grepafloxacin may cause dizziness. If you experience dizziness, avoid these activities.
What other drugs will affect grepafloxacin (Raxar)?
Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours before or 4 hours after a dose of grepafloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of grepafloxacin can greatly decrease the effects of the antibiotic.
Do not take grepafloxacin without first talking to your doctor if you are taking any of the following drugs:
- the heart medicines amiodarone (Cordarone), disopyramide (Norpace), quinidine (Cardioquin, Quinidex, Quinaglute, others), procainamide (Procan SR, Pronestyl), sotalol (Betapace), and bepridil (Vascor);
- terfenadine (Seldane, Seldane-D) or astemizole (Hismanal);
- a tricyclic antidepressant including amitriptyline (Elavil, Endep), amoxapine (Asendin), imipramine (Tofranil), nortriptyline (Pamelor), doxepin (Sinequan), and others;
- a phenothiazine including chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), and others;
- erythromycin (E-Mycin, Ery-Tab, E.E.S., others); or
- cisapride (Propulsid).
Grepafloxacin and the drugs listed above may affect the rhythm of your heartbeats. You may not be able to take grepafloxacin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Before taking grepafloxacin, tell your doctor if you are taking:
- warfarin (Coumadin);
- theophylline (Theo-Dur, Theolair, Slo-Phyllin, Slo-Bid, Elixophyllin, others);
- insulin or an oral diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Diabeta, Glynase), and others; or
- a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), and others.
You may not be able to take grepafloxacin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with grepafloxacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
Your pharmacist has additional information about grepafloxacin written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2009 Cerner Multum, Inc. Version: 5.04. Revision date: 2/22/07.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Raxar Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.