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Raxibacumab

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Raxibacumab

RAXIBACUMAB

(human IgG1λ monoclonal antibody) for Intravenous Infusion

DRUG DESCRIPTION

Raxibacumab is a human IgG1λ monoclonal antibody that binds the PA component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system.

Raxibacumab is supplied as a sterile, liquid formulation in single-dose vials for intravenous infusion. Each vial contains 1,700 mg/34 mL (50 mg/mL) raxibacumab in citric acid (0.13 mg/mL), glycine (18 mg/mL), polysorbate 80 [0.2 mg/mL (w/v)], sodium citrate (2.8 mg/mL), and sucrose (10 mg/mL), with a pH of 6.5. Raxibacumab is a clear to opalescent, colorless to pale yellow, liquid.

Last reviewed on RxList: 2/11/2016
This monograph has been modified to include the generic and brand name in many instances.

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