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Reactive Arthritis (cont.)

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What causes reactive arthritis?

As mentioned, reactive arthritis is felt in part to be genetic. There are certain genetic markers that are far more frequent in patients with reactive arthritis than in the normal population. For example, the HLA-B27 gene is commonly seen in patients with reactive arthritis. Even in patients who have the genetic background that predisposes them to developing reactive arthritis, however, exposure to certain infections seem to be required to trigger the onset of the disease.

Reactive arthritis can occur after venereal infections. The most common bacterium that has been associated with this post-venereal form of reactive arthritis is an organism called Chlamydia trachomatis. Reactive arthritis also occurs after infectious dysentery, with bacterial organisms in the bowel, such as Salmonella, Shigella, Yersinia, and Campylobacter. Typically, the arthritis develops one to three weeks after the onset of the bacterial infection. Reactive arthritis has also been reported associated with bladder infusions of BCG used for treating bladder cancer.

What are risk factors for developing reactive arthritis?

  • Gender: Reactive arthritis is more frequent in men between 20 and 40 years of age.
  • Hereditary factors: There are inherited genes, such as HLA-B27, that increase the risk for developing reactive arthritis.
  • Further risk factors include sexual promiscuity and exposure to bacteria that cause dysentery.

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Reactive Arthritis - Symptoms Question: What were the symptoms of your reactive arthritis?
Reactive Arthritis - Personal Experience Question: How old were you when you were diagnosed with reactive arthritis? Please share your experience.
Reactive Arthritis - Non-Joint Symptoms Question: What are your symptoms associated with reactive arthritis in non-joint areas?
Reactive Arthritis - Treatment Question: What kinds of treatment, therapy, or medication have been effective for your reactive arthritis?
Source: MedicineNet.com
http://www.medicinenet.com/reactive_arthritis/article.htm

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