Reclast (Zoledronic Acid Injection) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Reclast

Osteoporosis »

Osteoporosis facts

Osteoporosis is a condition of increased susceptibility to fracture due to fragile bone.
Osteoporosis weakens bone and increases risk of bone fracture.
Bone mass (bone density) decreases after 35 years of age and decreases more rapidly in women after menopause.
Key risk factors for osteoporosis include genetics, lack of exercise, lack of calcium and vitamin D, personal history of fracture as an adult, cigarette smoking, excessive alcohol consumption, history of rheumatoid arthritis, low body weight, and family history of osteoporosis.
Patients with osteoporosis have no symptoms until bone fractures occur.
The diagnosis of osteoporosis can be suggested by X-rays and confirmed by tests to measure bone density.
Treatments for osteoporosis, in addition to prescription osteoporosis medications, include stopping use of alcohol and cigarettes, and assur...

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Reclast Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Prescribing Information

For Patients

Reclast (zoledronic acid) is used to treat Paget's disease, high blood levels of calcium caused by cancer (hypercalcemia of malignancy, multiple myeloma (a type of bone marrow cancer) or cancer that has spread from elsewhere in the body to the bone, to treat or prevent osteoporosis in postmenopausal women, and to increase bone mass in men with osteoporosis. It is also used to treat or prevent osteoporosis in people who will be taking certain steroid medicines for 12 months or longer. It is in a group of medicines called bisphosphonates. Common side effects include nausea, tiredness, flu-like symptoms (e.g., fever, chills, muscle/joint aches), dizziness, headache, or pain/redness/swelling at the injection site. Most of these side effects occur within 3 days of treatment.

Reclast is given intravenously. Dose varies depending on the condition being treated. Recommended doses: For treatment of postmenopausal osteoporosis, a single 5 mg infusion once/year; for prevention of postmenopausal osteoporosis 5 mg every two years; for Paget's disease of bone a single 5 mg infusion; for prevention or treatment of steroid-induced osteoporosis, 5 mg once/year. Reclast may interact with diuretics (water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, or non-steroidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications you are taking. Reclast should not be used during pregnancy. It may harm a fetus. It is unknown if this medication passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Our Reclast (zoledronic acid) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Reclast Prescribing Information: Indications & Dosage

Reclast®
(zoledronic acid) Structural Formula Illustration

Treatment of Osteoporosis in Postmenopausal Women

Reclast is indicated for treatment of osteoporosis in postmenopausal women. In postmenopausal women with osteoporosis, diagnosed by bone mineral density (BMD) or prevalent vertebral fracture, Reclast reduces the incidence of fractures (hip, vertebral and non-vertebral osteoporosis-related fractures). In patients at high risk of fracture, defined as a recent low-trauma hip fracture, Reclast reduces the incidence of new clinical fractures [see Clinical Studies].

Prevention of Osteoporosis in Postmenopa...

Read the complete drug monograph for Reclast »

What is Reclast Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Reclast Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

urinating less than usual or not at all;
muscle spasms, numb or tingly feeling (especially around your mouth);
fever, chills, body aches, flu symptoms;
pale skin, easy bruising, unusual weakness;
severe joint, bone, or muscle pain; or
bronchospasm (wheezing, chest tightness, trou...

Read the complete patient information for Reclast »

What is Reclast Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Reclast Consumer Information: Uses

This medication is used to treat a certain type of bone disease (Paget's disease) that causes abnormal and weak bones. Zoledronic acid is also used to treat bone loss (osteoporosis) in men and in women after menopause. It may also be used to treat or prevent osteoporosis in people who are taking corticosteroid medications (such as prednisone) for long periods. It works by slowing the breakdown of bone and keeping bones strong. It also helps to reduce the risk of broken bones (fractures). This medication belongs to a class of drugs known as bisphosphonates.

Another zoledronic acid product is...

Read the complete consumer information for Reclast »