Recommended Topic Related To:

Reclast

"May 4, 2011 -- The osteoporosis drugs known as bisphosphonates increase the risk of getting unusual thigh bone fractures, as experts have suspected, according to a new Swedish study.

But these fractures are infrequent and the risk is "...

Reclast

Overdosage
Contraindications

OVERDOSE

Clinical experience with acute overdosage of zoledronic acid (Reclast) solution for intravenous infusion is limited. Patients who have received doses higher than those recommended should be carefully monitored. Overdosage may cause clinically significant renal impairment, hypocalcemia, hypophosphatemia, and hypomagnesemia. Clinically relevant reductions in serum levels of calcium, phosphorus, and magnesium should be corrected by intravenous administration of calcium gluconate, potassium or sodium phosphate, and magnesium sulfate, respectively.

Single doses of Reclast should not exceed 5 mg and the duration of the intravenous infusion should be no less than 15 minutes [see DOSAGE AND ADMINISTRATION].

CONTRAINDICATIONS

Reclast is contraindicated in patients with the following conditions:

  • Hypocalcemia [see WARNINGS AND PRECAUTIONS]
  • Creatinine clearance less than 35 mL/min and in those with evidence of acute renal impairment due to an increased risk of renal failure [see WARNINGS AND PRECAUTIONS].
  • Known hypersensitivity to zoledronic acid or any components of Reclast. Hypersensitivity reactions including urticaria, angioedema, and anaphylactic reaction/shock have been reported [see Post-Marketing Experience].

Last reviewed on RxList: 5/6/2013
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
A A A

Reclast - User Reviews

Reclast User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Reclast sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Healthy Bones

Get tips and advances in treatment.


NIH talks about Ebola on WebMD