Brand Names: Metozolv ODT, Reglan

Generic Name: metoclopramide (Pronunciation: MET oh KLOE pra mide)

• What is metoclopramide (Reglan)?
• What are the possible side effects of metoclopramide (Reglan)?
• What is the most important information I should know about metoclopramide (Reglan)?
• What should I discuss with my healthcare provider before taking metoclopramide (Reglan)?
• How should I take metoclopramide (Reglan)?
• What happens if I miss a dose (Reglan)?
• What happens if I overdose (Reglan)?
• What should I avoid while taking metoclopramide (Reglan)?
• What other drugs will affect metoclopramide (Reglan)?
• Where can I get more information?

What is metoclopramide (Reglan)?

Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.

Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief of symptoms.

Metoclopramide is also used to treat slow gastric emptying in people with diabetes (also called diabetic gastroparesis), which can cause nausea, vomiting, heartburn, loss of appetite, and a feeling of fullness after meals.

Metoclopramide may also be used for purposes not listed in this medication guide.

Metoclopramide 10 mg-APH

round, white, imprinted with INV 264

Metoclopramide 10 mg-BAR

round, white, imprinted with PLIVA 430

Metoclopramide 10 mg-TEV

round, white, imprinted with BL, 93

Metoclopramide 5 mg-BAR

round, green, imprinted with PLIVA 517

Metoclopramide 5 mg-MUT

round, white, imprinted with MP 148

Metoclopramide 5 mg-QUA

oval, white, imprinted with 4234, LOGO

Metoclopramide 5 mg-TEV

round, white, imprinted with BL, 92

Metoclopramine 5 mg-APH

round, white, imprinted with INV 263

Reglan 10 mg

oblong, white, imprinted with REGLAN, AHR 10

Reglan 5 mg

oval, green, imprinted with REGLAN 5, SP

What are the possible side effects of metoclopramide (Reglan)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

• tremors, or restless muscle movements in your eyes, tongue, jaw, neck, arms, or legs;
• mask-like appearance of the face;
• very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
• depressed mood, thoughts of suicide or hurting yourself;
• hallucinations, anxiety, agitation, jittery feeling, trouble staying still;
• swelling, fluid retention;
• jaundice (yellowing of your skin or eyes); or
• seizure (convulsions).

Less serious side effects may include:

• feeling restless, drowsy, tired, or dizzy;
• headache, sleep problems (insomnia);
• nausea, vomiting, diarrhea;
• breast tenderness or swelling;
• changes in your menstrual periods; or
• urinating more than usual.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Reglan (metoclopramide) Side Effects Center for a complete guide to possible side effects »

What is the most important information I should know about metoclopramide (Reglan)?

You should not take this medication if you are allergic to metoclopramide, or if you have bleeding or blockage in your stomach or intestines, epilepsy or other seizure disorder, or an adrenal gland tumor (pheochromocytoma).

Before you take metoclopramide, tell your doctor if you have kidney or liver disease, congestive heart failure, high blood pressure, diabetes, Parkinson's disease, or a history of depression.

Stop using metoclopramide and call your doctor at once if you have tremors or uncontrolled muscle movements, fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing, depressed mood, thoughts of suicide or hurting yourself, hallucinations, anxiety, agitation, seizure, or jaundice (yellowing of your skin or eyes).