What is the swine flu (H1N1 influenza A virus) and what causes it?
The 2009 swine flu virus (otherwise known as H1N1
influenza) is caused by an H1N1
influenza A virus. H1N1 influenza viruses are the normal cause of influenza in
humans and may also infect other animals, including pigs. This particular
variant is an example of a virus that likely originated in swine and has mutated
(changed its biological characteristics) so it is now affecting humans.
What are the symptoms of swine flu (H1N1 influenza A virus)?
Symptoms
of swine flu vary widely and are similar to symptoms of seasonal flu. Infected
individuals may experience
fever,
cough,
sore throat,
body aches,
headache,
chills, and
fatigue.
Vomiting and diarrhea have been reported and severe cases
may result in respiratory failure and even death.
Zanamivir is an antiviral medication. It blocks the actions of viruses in your body.
Zanamivir is used to treat flu symptoms caused by influenza virus in patients who have had symptoms for less than 2 days. Zanamivir may also be given to prevent influenza in people who may be exposed but do not yet have symptoms. Zanamivir will not treat the common cold.
Zanamivir may also be used for purposes other than those listed in this medication guide.
What are the possible side effects of zanamivir (Relenza)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Some people using zanamivir have had rare side effects of confusion, delirium and self-injury. These symptoms have occurred most often in children. It is not known whether zanamivir was the exact cause of these symptoms. However, anyone using zanamivir should be watched closely for signs of confusion or unusual behavior. Call a doctor at once if you or the child using zanamivir has any of these symptoms.
Stop using zanamivir and call your doctor at once if you have wheezing or severe breathing problems.
Less serious side effects may include:
headache;
dizziness;
nausea, vomiting, or diarrhea;
infection of your ear, nose, or throat;
stuffy or irritated nose; or
cough or respiratory symptoms.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about zanamivir (Relenza)?
Do not use a nebulizer or ventilator to give zanamivir. Zanamivir inhalation powder should never be mixed with a liquid.
Zanamivir is used to treat flu symptoms caused by influenza virus in patients who have had symptoms for less than 2 days. Zanamivir may also be given to prevent influenza in people who may be exposed but do not yet have symptoms. Zanamivir will not treat the common cold.
Treatment with zanamivir should start as soon as possible when flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.
Do not use this medication to treat flu symptoms in a child younger than 7 years old. Children as young as 5 may use the medication to prevent flu symptoms.
Do not use an inhaled nasal flu vaccine (FluMist) within 2 weeks before or 48 hours after using zanamivir. Zanamivir may interfere with the drug action of FluMist, making the vaccine less effective. Follow your doctor's instructions.
Before using zanamivir, tell your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition. Serious or life-threatening bronchospasm (difficulty breathing) and other effects on the lungs can occur while using zanamivir. Stop using zanamivir and call your doctor at once if you have wheezing or severe breathing problems.
If you have asthma, COPD, or other chronic lung disease, make sure you have a fast-acting inhaled bronchodilator available to treat any serious breathing problems that may occur while using zanamivir. Fast-acting bronchodilators include albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), and pirbuterol (Maxair). Talk with your doctor about which medicine is best for you.
Some people using zanamivir have had rare side effects of confusion, delirium and self-injury. These symptoms have occurred most often in children. It is not known whether zanamivir was the exact cause of these symptoms. However, anyone using zanamivir should be watched closely for signs of confusion or unusual behavior. Call a doctor at once if you or the child using zanamivir has any of these symptoms.
Zanamivir should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.