"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
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Details with Side Effects
During clinical trials of RELISTOR administered subcutaneously, no cases of methylnaltrexone bromide overdose were reported. A study of healthy volunteers noted orthostatic hypotension associated with a dose of 0.64 mg/kg administered as an intravenous bolus.
Signs or symptoms of orthostatic hypotension should be monitored, and treatment should be initiated, as appropriate.
RELISTOR is contraindicated in patients with known or suspected mechanical gastrointestinal obstruction.
Last reviewed on RxList: 9/19/2013
This monograph has been modified to include the generic and brand name in many instances.
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