Remodulin (Treprostinil Sodium) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

May 26, 2012

Remodulin

High Blood Pressure »

High blood pressure facts

High blood pressure (hypertension) is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mm Hg.
High blood pressure is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs.
Poorly controlled high blood pressure ultimately can cause damage to blood vessels in the eye, thickening of the heart muscle and heart attacks, hardening of the arteries (arteriosclerosis), kidney failure, and strokes.
Most antihypertensive medications can be used alone or in combination. Some are used only in combination. Some are preferred over others in certain specific medical situations. And some are not to be used (contraindicated) in other situations.
Several classes of antihypertensive medications are available, including ACE i...

Read the High Blood Pressure article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Remodulin User Reviews >>

Remodulin

High Blood Pressure (Hypertension) Slideshow

Take the Salt Quiz!

Lowering Blood Pressure Exercise Tips Pictures

font size

REMODULIN®
(treprostinil) Injection

DRUG DESCRIPTION

Remodulin (treprostinil) Injection is a sterile solution of treprostinil formulated for subcutaneous or intravenous administration. Remodulin (treprostinil sodium) is supplied in 20 mL multidose vials in four strengths, containing 20 mg, 50 mg, 100 mg, or 200 mg (1 mg/mL, 2.5 mg/mL, 5 mg/mL or 10 mg/mL) of treprostinil. Each mL also contains 5.3 mg sodium chloride (except for the 10 mg/mL strength which contains 4.0 mg sodium chloride), 3 mg metacresol, 6.3 mg sodium citrate, and water for injection. Sodium hydroxide and hydrochloric acid may be added to adjust pH between 6.0 and 7.2.

Treprostinil is chemically stable at room temperature and neutral pH.

Treprostinil is (1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1Hbenz[f]inden-5-yl]oxy]acetic acid. Treprostinil has a molecular weight of 390.52 and a molecular formula of C₂₃H₃₄O₅.

The structural formula of treprostinil is: REMODULIN® (treprostinil) Injection Package Insert

REMODULIN® (treprostinil) Structural Formula Illustration

What are the possible side effects of treprostinil injection (Remodulin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

new or worsening PAH symptoms such as feeling short of breath (even with mild exertion), tiredness, chest pain, and pale skin;
swelling in your hands or feet; or
feeling like you might pass out.

Less serious side effects may include:

...

Read All Potential Side Effects and See Pictures of Remodulin »

What are the precautions when taking treprostinil sodium (Remodulin)?

Before using treprostinil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, bleeding problems.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Caution is advised when using this drug in the elderly...

Read All Potential Precautions of Remodulin »

Last reviewed on RxList: 4/4/2011
This monograph has been modified to include the generic and brand name in many instances.