May 25, 2017
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Remodulin Patient Information Including Side Effects

Brand Names: Remodulin

Generic Name: treprostinil injection (Pronunciation: tre PROS ti nil)

What is treprostinil injection (Remodulin)?

Treprostinil dilates (or widens) the arteries and decreases the amount of blood clotting platelets in your body. These effects lower blood pressure in the pulmonary artery that leads from the heart to the lungs.

Treprostinil is used to treat pulmonary arterial hypertension (PAH). It improves your ability to exercise and prevents your condition from getting worse.

Treprostinil may also be used for other purposes not listed in this medication guide.

What are the possible side effects of treprostinil injection (Remodulin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • new or worsening PAH symptoms such as feeling short of breath (even with mild exertion), tiredness, chest pain, and pale skin;
  • swelling in your hands or feet; or
  • feeling like you might pass out.

Less serious side effects may include:

  • pain, swelling, redness, bleeding, or a hard lump where your catheter is placed;
  • dizziness;
  • mild skin rash;
  • headache or jaw pain;
  • flushing (warmth, redness or tingling); or
  • diarrhea or nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Remodulin (treprostinil sodium) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about treprostinil injection (Remodulin)?

Before using this medication, tell your doctor if you have low blood pressure, liver disease, or a bleeding or blood clotting disorder.

Treprostinil is given as an continuous (around-the-clock) injection using an infusion pump. The medicine enters the body through a catheter placed under your skin or into a vein. Your doctor, nurse, or pharmacist will give you specific instructions on how to use an infusion pump and inject your medicine.

Your doctor may want you to be in a hospital when you start using treprostinil. This is so you can be watched for any signs of serious side effects from the medicine.

You will probably have to use this medicine for several months or years to control your condition and keep it from getting worse.

Use treprostinil regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. Make sure you have a backup infusion pump and infusion sets available so as not to interrupt your treatment if one infusion pump stops working.

Call your doctor if your symptoms do not improve or if they get worse.

Side Effects Centers

Remodulin - User Reviews

Remodulin User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Remodulin sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Get tips on handling your hypertension.