"Proton pump inhibitors (PPIs) are associated with increased risk for chronic kidney disease (CKD), according to two population-based analyses published online January 11 in JAMA Internal Medicine. The authors suggest the widely used drugs "...
Renagel has been given to normal healthy volunteers in doses of up to 14 grams per day for eight days with no adverse effects. Renagel has been given in average doses up to 13 grams per day to hemodialysis patients. There are no reports of overdosage with Renagel in patients. Since Renagel is not absorbed, the risk of systemic toxicity is low.
Renagel is contraindicated in patients with bowel obstruction.
Renagel is contraindicated in patients with known hypersensitivity to sevelamer hydrochloride or to any of the excipients.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 3/25/2016
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