Renova 0.02% (Tretinoin Cream) Drug Overview and Uses for Patients and Caregivers at RxList

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May 27, 2012

Renova 0.02%

Wrinkles »

Wrinkles facts

Skin ages all over the body but much more so where there has been sun exposure. Changes brought on by sun damage (photoaging) include "dryness" (really roughness), sagginess, skin growths like keratoses ("liver spots"), and wrinkles.
Wrinkles in turn can be divided into two categories: fine surface lines and deep furrows. Wrinkle treatments are in general much more effective for fine lines. Deeper creases may require more aggressive techniques, such as plastic surgery.
Factors that promote wrinkling include smoking, skin type (people with light-colored skin and blue eyes are more susceptible to sun damage), heredity (some families wrinkle more), hairstyle (depending on how much skin is covered by hair and protected from the sun), dress (again, by determining which skin is exposed), and occupational and recreational sun exposure over the course of many years.

Read the Wrinkles article »

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Renova 0.02%

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RENOVA®
(tretinoin) Cream 0.02%

FOR TOPICAL USE ON THE FACE. NOT FOR OPHTHALMIC, ORAL, OR INTRAVAGINAL USE.

DRUG DESCRIPTION

RENOVA (tretinoin cream) 0.02% contains the active ingredient tretinoin in a cream base. Tretinoin is a yellow- to light-orange crystalline powder having a characteristic floral odor. Tretinoin is soluble in dimethylsulfoxide, slightly soluble in polyethylene glycol 400, octanol, and 100% ethanol. It is practically insoluble in water and mineral oil, and it is insoluble in glycerin. The chemical name for tretinoin is (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1 -cyclonexen-1 -yl)-2,4,6,8-nonatetraenoic acid. Tretinoin is also referred to as all-trans-ret inoic acid and has a molecular weight of 300.44. The structural formula is represented below.

RENOVA (tretinoin) structural formula illustration

Tretinoin is available as RENOVA (tretinoin cream) at a concentration of 0.02% w/w in an oil-in-water emulsion formulation consisting of benzyl alcohol, butylated hydroxytoluene, caprylic/capric triglyceride, cetyl alcohol, edetate disodium, fragrance, methylparaben, propylparaben purified water, stearic acid, stearyl alcohol, steareth 2, steareth 20: and xanthan gum.

Last reviewed on RxList: 12/10/2008
This monograph has been modified to include the generic and brand name in many instances.