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"Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

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Rescriptor Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking delavirdine (Rescriptor)?

Do not use this medication if you are allergic to delavirdine, or if you are using any of the following drugs:

  • alprazolam (Xanax), midazolam (Versed) or triazolam (Halcion);
  • pimozide (Orap); or
  • ergot medicine such as ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine).

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking delavirdine, tell your doctor if you have:

  • liver disease;
  • high cholesterol or triglycerides;
  • low stomach acid production; or
  • if you have ever taken efavirenz (Sustiva) or nevirapine (Viramune) and they were not effective in treating your condition.

FDA pregnancy category C. It is not known whether delavirdine is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant.

Your name may need to be listed on an antiviral pregnancy registry when you start using delavirdine. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether delavirdine had any effect on the baby.

You should not breast-feed while you are using delavirdine. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.

How should I take delavirdine (Rescriptor)?

Take delavirdine exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Do not take delavirdine as your only HIV medication. HIV/AIDS is usually treated with a combination of different drugs. Your disease may become resistant to delavirdine if you do not take it in combination with other HIV medicines your doctor has prescribed.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Take this medicine with a full glass of water.

Delavirdine can be taken with or without food.

If you have a condition of decreased stomach acid, your doctor may recommend taking delavirdine with an acidic beverage such as orange or cranberry juice.

The 100-milligram delavirdine tablets may be dissolved in water to make swallowing easier. Place 4 tablets into at least 3 ounces (just under 1/3 cup) of water. Let the liquid stand for a few minutes, then stir to allow the tablets to disperse evenly in the liquid. Drink this mixture right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

The 200-milligram delavirdine tablet must be swallowed whole. Do not crush, chew, or disperse the tablet in water.

It is important to take delavirdine regularly to get the most benefit. Get your prescriptions refilled before you run out of medicine completely.

To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your liver function may also need to be tested. It is important that you not miss any scheduled visits to your doctor.

Store delavirdine at room temperature away from moisture and heat.

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Rescriptor - User Reviews

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