Rescula (Unoprostone isopropyl) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Rescula

Glaucoma »

What is glaucoma?

Glaucoma is a disease of the major nerve of vision, called the optic nerve. The optic nerve receives light-generated nerve impulses from the retina and transmits these to the brain, where we recognize those electrical signals as vision. Glaucoma is characterized by a particular pattern of progressive damage to the optic nerve that generally begins with a subtle loss of side vision (peripheral vision). If glaucoma is not diagnosed and treated, it can progress to loss of central vision and blindness.

Glaucoma is usually, but not always, associated with elevated pressure in the eye (intraocular pressure). Generally, it is this elevated eye pressure that leads to damage of the eye (optic) nerve. In some cases, glaucoma may occur in the presence of normal eye pressure. This form of glaucoma is believed to be caused by poor regulation of blood flow to the optic nerve.

How common is glaucoma?

Worldwide, glaucoma...

Read the Glaucoma article »

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Rescula

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

RESCULA (unoprostone isopropyl) ^â

(unoprostone isopropyl ophthalmic solution) 0.15%

DRUG DESCRIPTION

Unoprostone Isopropyl is a docosanoid, a structural analogue of an inactive biosynthetic cyclic derivative of arachidonic acid, 13, 14-dihydro-15-keto-prostaglandin F_2a. Its chemical name is isopropyl (+)-(Z)-7-[(1R, 2R, 3R, 5S)-3,5-dihydroxy-2-(3-oxodecyl) cyclopentyl] -5-heptenoate. Its molecular formula is C₂₅H₄₄O_5.

Unoprostone isopropyl is a clear, colorless viscous liquid that is very soluble in acetonitrile, ethanol, ethyl acetate, isopropanol, dioxane, ether, and hexane. It is practically insoluble in water. RESCULA^â (unoprostone isopropyl ophthalmic solution) 0.15% is supplied as a sterile, isotonic, buffered aqueous solution of unoprostone isopropyl with a pH of 5.0 6.5 and an osmolality of 235 - 300 mOsmol/kg.

Each mL of Rescula contains 1.5 mg of unoprostone isopropyl. Benzalkonium chloride 0.015% is added as a preservative. Inactive ingredients are: mannitol, polysorbate 80, edetate disodium, sodium hydroxide or hydrochloric acid (to adjust pH), and water for injection.

What are the possible side effects of unoprostone ophthalmic (Rescula)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using unoprostone ophthalmic and call your doctor at once if you have any of these serious side effects: