Restasis (Cyclosporine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Restasis

Sjogren's Syndrome »

Sjögren's syndrome facts

Sjögren's syndrome is an autoimmune disease.
Sjögren's syndrome involves inflammation of glands and other tissues of the body.
About 90% of Sjögren's syndrome patients are female.
Sjögren's syndrome can be complicated by infections of the eyes, breathing passages, and mouth.
Sjögren's syndrome is typically associated with antibodies against a variety of body tissues (autoantibodies).
Diagnosis of Sjögren's syndrome can be aided by a saliva-gland biopsy.
Treatment of patients with Sjögren's syndrome is directed toward the particular areas of the body that are involved and complications, such as infection.

What is Sjögren's syndrome?

SjÃ¶gren's syndrome is an autoimmune disease characterized by dryness of the mouth and eyes. Autoimmune diseases feature the abnormal pr...

Read the Sjogren's Syndrome article »

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Restasis

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RESTASIS®
(cyclosporine) Ophthalmic Emulsion 0.05%
Sterile, Preservative-Free

DRUG DESCRIPTION

RESTASIS® (cyclosporine ophthalmic emulsion) 0.05% contains a topical immunomodulator with anti-inflammatory effects. Cyclosporine's chemical name is Cyclo[[(E)-(2S,3R,4R)-3- hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-Lleucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-Nmethyl-L-valyl] and it has the following structure:

Structural Formula:

Formula: C₆₂H₁₁₁N₁₁O₁₂ Mol. Wt.:1202.6

Cyclosporine is a fine white powder. RESTASIS® (cyclosporine) appears as a white opaque to slightly translucent homogeneous emulsion. It has an osmolality of 230 to 320 mOsmol/kg and a pH of 6.5-8.0. Each mL of RESTASIS® (cyclosporine) ophthalmic emulsion contains: Active: cyclosporine 0.05%. Inactives: glycerin; castor oil; polysorbate 80; carbomer copolymer type A; purified water; and sodium hydroxide to adjust pH.

What are the possible side effects of cyclosporine ophthalmic (Restasis)?

Serious side effects are not expected to occur during treatment with this medication.

Eye burning, redness, tearing, discharge, pain, itching, stinging, or visual blurring may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

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What are the precautions when taking cyclosporine (Restasis)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an eye infection.

Before using this medication, tell your doctor or pharmacist your medical history.

This drug may cause blurred vision. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss...

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Last reviewed on RxList: 7/9/2010
This monograph has been modified to include the generic and brand name in many instances.