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Restless Leg Syndrome (cont.)

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What is the treatment for restless leg syndrome?

Treatment of restless leg syndrome is first directed toward any underlying illness, if known. For example:

  • Blood testing to reveal underlying iron deficiency anemia may reveal the underlying cause.
  • If varicose veins are thought to be the cause, then surgery to repair the circulation may be considered.
  • Reduction or elimination of caffeine, nicotine, and alcohol from a person's diet can be very helpful.
  • Stopping smoking can significantly diminish or prevent symptoms.
  • Getting better sleep and exercise can help some persons affected by restless legs.
  • Pregnant women who do not sleep well at night and other people with sleep disorders may develop RLS.

What medications are used to treat restless leg syndrome?

Medications used to treat restless leg syndrome include:

  • natural supplements (such as iron),
  • carbidopa-levodopa (Sinemet),
  • opioids (such as hydrocodone, or tramadol [Ultram] for intermittent symptoms),
  • carbamazepine (Tegretol, Tegretol XR, Equetro, Carbatrol),
  • clonazepam (Klonopin),
  • diazepam (Valium),
  • triazolam (Halcion),
  • temazepam (Restoril),
  • baclofen (Lioresal)
  • bromocriptine,
  • clonidine (Catapres, Catapres-TTS, Jenloga),
  • gabapentin (Neurontin),
  • gabapentin enacarbil (Horizant ER),
  • ropinirole (Requip), and
  • pramipexole (Mirapex).
Medically Reviewed by a Doctor on 7/9/2014


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