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home > drugs a-z list > retrovir (zidovudine) drug center
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Retrovir
HIV and AIDS: Antiretroviral Drugs, Treatments and Medications »
Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist
Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.
Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.
CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...
Read the HIV and AIDS: Antiretroviral Drugs, Treatments and Medications article »
Retrovir
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Retrovir Drug Center
Medical Editor: John P. Cunha, DO, FACOEP
Retrovir (zidovudine) is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). It is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Retrovir is not a cure for HIV or AIDS. It is an antiviral medication. This medication is available in generic form. Common side effects include headache, nausea, vomiting, trouble sleeping, or loss of appetite.
The recommended adult oral dose of Retrovir is 600 mg/day in divided doses in combination with other antiretroviral agents. The pediatric dose of Retrovir is based on the child's weight. Retrovir may interact with atovaquone, doxorubicin, fluconazole, ganciclovir, interferon-alfa, methadone, nelfinavir, phenytoin, probenecid, ribavirin, ritonavir, or stavudine. Tell your doctor all medications you use. During pregnancy, Retrovir should be used only when prescribed. However, HIV medicines are often given to pregnant women with HIV. Treatment decreases the risk of HIV transmission to the baby. This medication passes into breast milk. Because breast milk can transmit HIV, do not breast-feed.
Our Retrovir (zidovudine) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Retrovir Prescribing Information: Indications & Dosage
Treatment of HIV-1
RETROVIR, a nucleoside reverse transcriptase inhibitor, is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.
Prevention of Maternal-Fetal HIV-1 Transmission
RETROVIR is indicated for the prevention of maternal-fetal HIV-1 transmission [see DOSAGE AND ADMINISTRATION]. The indication is based on a dosing regimen that included 3 components:
- antepartum therapy of HIV-1 infected mothers
- intrapartum therapy of HIV-1 infected mothers
- post-partum ther...
Read the complete drug monograph for Retrovir »
What is Retrovir Prescribing Information?
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Retrovir Patient Information: Side Effects
Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:
- liver damage - nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- lactic acidosis - muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, and fast or uneven hea...
Read the complete patient information for Retrovir »
What is Retrovir Patient Information?
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Retrovir Consumer Information: Uses
This drug is used with other medications to help control your HIV infection, thereby improving your quality of life. It may also lower your risk of complications from HIV (such as new infections, cancers). Zidovudine belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTIs.
Zidovudine is used in pregnant women to prevent passing the HIV virus to the unborn baby. This medication is also used in newborns born to mothers infected with HIV to prevent infection in the newborns.
Zidovudine is not a cure for HIV infection and it does not prevent the spread of HIV t...
Read the complete consumer information for Retrovir »
What is Retrovir Consumer Information?
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Next: Drug Description
Additional Retrovir Information
Retrovir - User Reviews
Retrovir User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Retrovir sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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