"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended 150 mg lamivudine/300 mg raltegravir (Dutrebis, Merck Sharp & Dohme Limited) for the treatment of HIV 1 infection in adults, adolesce"...
Retrovir IV Patient Information Including Side Effects
Brand Names: Retrovir
Generic Name: zidovudine (injection) (Pronunciation: zye DOE vyoo deen)
- What is zidovudine injection (Retrovir IV)?
- What are the possible side effects of zidovudine injection (Retrovir IV)?
- What is the most important information I should know about zidovudine injection (Retrovir IV)?
- What should I discuss with my healthcare provider before using zidovudine injection (Retrovir IV)?
- How should I use zidovudine injection (Retrovir IV)?
- What happens if I miss a dose (Retrovir IV)?
- What happens if I overdose (Retrovir IV)?
- What should I avoid while using zidovudine injection (Retrovir IV)?
- What other drugs will affect zidovudine injection (Retrovir IV)?
- Where can I get more information?
What is zidovudine injection (Retrovir IV)?
Zidovudine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Zidovudine injection is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Zidovudine is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Zidovudine is not a cure for HIV or AIDS.
Zidovudine may also be used for purposes not listed in this medication guide.
What are the possible side effects of zidovudine injection (Retrovir IV)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.
Stop using zidovudine and call your doctor at once if you have any of these other serious side effects:
- severe muscle pain;
- signs of a new infection such as fever, chills, body aches, flu symptoms, sores in your mouth and throat;
- pale skin, feeling light-headed, rapid heart rate, trouble concentrating;
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
- increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia);
- diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;
- swelling in your neck or throat (goiter);
- problems with walking, breathing, speech, swallowing, or eye movement;
- weakness or prickly feeling in your fingers or toes;
- severe lower back pain, loss of bladder or bowel control;
- liver problems--upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or
- severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
- sleep problems (insomnia);
- mild nausea, constipation;
- joint pain;
- headache; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Retrovir IV (zidovudine injection) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about zidovudine injection (Retrovir IV)?
Do not use this medication if you have ever had an allergic reaction to Retrovir or any medicine that contains zidovudine, including Combivir or Trizivir.
Some people develop lactic acidosis while using zidovudine. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.
This medication can also cause severe or life-threatening effects on your liver. Call your doctor at once if you have any of these symptoms while using zidovudine: pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Zidovudine can lower blood cells that help your body fight infections and help your blood clot. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection.
Do not use Retrovir with any other medicine that contains zidovudine or stavudine, including: Combivir, Trizivir, or Zerit.
Additional Retrovir IV Information
- Retrovir IV Drug Interactions Center: zidovudine iv
- Retrovir IV Side Effects Center
- Retrovir IV Overview including Precautions
- Retrovir IV FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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