Revatio (Sildenafil Citrate) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Revatio

Pulmonary Hypertension »

What are pulmonary arteries?

The human body has two major sets of blood vessels that distribute blood from the heart to the body. One set pumps blood from the right heart to the lungs and the other from the left heart to the rest of the body.

The portion of the circulation that distributes oxygen-rich blood from the left side of the heart, throughout the body, is referred to as the systemic circulation.
The blood then returns from the body to the right side of the heart and passes through the lungs to replenish oxygen.
It then returns to the left side of the heart for another round through the systemic circulation.
The portion of the circulation that distributes the blood from the right side of the heart to the lungs is referred to as the pulmonary (lung) circulation.
The pulmonary arteries are the major blood vessels that carry blood from the rig...

Read the Pulmonary Hypertension article »

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Revatio Drug Center

Medical Editor: Charles Patrick Davis, MD, PhD

Prescribing Information

For Patients

Revatio Overview

Revatio (sildenafil), a cyclic GMP inhibitor, is indicated for the treatment of pulmonary arterial hypertension to improve exercise ability and delay clinical worsening. Also used to treat erectile dysfunction. Revatio may be available as a generic after September, 2012. Some of the side effects of Revatio may include but are not limited to low blood pressure and may cause faint feeling or dizziness, shortness of breath.

Revatio is available in 20 mg strength tablets. The recommended dose of Revatio is 20 mg three times a day. Revatio should be taken approx. 4-6 hours apart. Use of Revatio with nitrates in any form is contraindicated. Use of Revatio with ritonavir and other potent CYP3A inhibitors is not advised. Use caution when co-administering alpha-blockers with Revatio because of additive blood pressure-lowering effects. No adequate and well-controlled studies of sildenafil in pregnant women. Revatio should be used during pregnancy only if clearly needed. Caution should be exercised when Revatio is given to nursing women.

Our Revatio (sildenafil) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Revatio Prescribing Information: Indications & Dosage

Revatio (sildenafil) Structural Formula Illustration

REVATIO (sildenafil citrate) ® is indicated for the treatment of pulmonary arterial hypertension (WHO Group I) to improve exercise ability and delay clinical worsening. The delay in clinical worsening was demonstrated when REVATIO (sildenafil citrate) was added to background epoprostenol therapy.

Studies establishing effectiveness included predominately patients with NYHA Functional Class II-III symptoms and etiologies of primary pulmonary hypertension (71%) or pulmonary hypertension associated with connective tissue disease (25%).

Limitation of Use/h...

Read the complete drug monograph for Revatio »

What is Revatio Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Revatio Consumer Information: Uses

Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction) by blocking a certain enzyme (phosphodiesterase-PDE5) in the body. In combination with sexual stimulation, sildenafil works by helping the blood flow into the penis to achieve and maintain an erection.

This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.

OTHER USES: This section contains uses of...

Read the complete consumer information for Revatio »