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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Revex Patient Information including How Should I Take

What should I discuss with my health care provider before receiving nalmefene (Revex)?

If possible, before you receive nalmefene, tell your doctor if you are allergic to any drugs, or if you have:

  • a history of addiction to narcotics;
  • liver disease;
  • kidney disease; or
  • heart disease (especially if you take heart medications).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. However opioid medications are not recommended for use during pregnancy.

Nalmefene may pass into breast milk and could harm a nursing baby. If possible, tell your caregivers if you are breast-feeding a baby.

In an overdose situation, it may not be possible before you are treated with nalmefene to tell your caregivers about any health conditions you have or if you are pregnant or breast-feeding. However, make sure any doctor caring for your pregnancy or your baby knows that you have received nalmefene, and if you were treated for a narcotic overdose.

How is nalmefene given (Revex)?

Nalmefene is given as an injection through a needle placed into a vein or muscle. You will receive this injection in a hospital or emergency setting.

After treatment with nalmefene, you will be watched to make sure the medication has been effective and you no longer have any effects of the opioid.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Emotional Wellness

Get tips on therapy and treatment.