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Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: drugs for irregular heartbeat (such as amiodarone, quinidine), beta-blockers (such as propranolol, atenolol, metoprolol), certain chemotherapy drugs (dasatinib, lapatinib, sunitinib, temsirolimus), digoxin, eletriptan, eplerenone, etravirine, warfarin.

Other medications can affect the removal of atazanavir from your body, which may affect how atazanavir works. Examples include St. John's wort, rifamycins (such as rifabutin), certain anti-seizure drugs (carbamazepine, phenobarbital), other HIV drugs (such as delavirdine, indinavir, ritonavir, tenofovir), among others.

Atazanavir can slow down or speed up the removal of other medications from your body, which may affect how they work. Examples of affected drugs include bepridil, cisapride, clarithromycin, fluticasone (inhaled through the mouth or nose), irinotecan, pimozide, ranolazine, trazodone, certain benzodiazepines (midazolam, triazolam), calcium channel blockers (such as diltiazem, verapamil), ergot alkaloids (such as dihydroergotamine, ergonovine, ergotamine, methylergonovine), certain drugs that weaken the immune system (cyclosporine, tacrolimus, sirolimus), drugs to treat erectile dysfunction/pulmonary hypertension (such as sildenafil, vardenafil), certain "statin" cholesterol drugs (lovastatin, rosuvastatin, simvastatin), medicines for depression (tricyclics such as amitriptyline), among others.

Check the labels on all the medicines you use for heartburn, indigestion, or ulcers (including prescription or nonprescription antacids, proton pump inhibitors such as omeprazole, H2 blockers such as ranitidine). These medications may prevent your HIV drugs from working. Ask your doctor or pharmacist about using those products safely.

This medication may decrease the effectiveness of hormonal birth control products (such as pills, patch, ring). This effect can result in pregnancy. However, to reduce the risk of spreading HIV to others, always use barrier protections during all sexual activity. (See also Notes section.)

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe dizziness or lightheadedness.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (e.g., liver function, bilirubin, lipid/cholesterol, EKG, blood sugar) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

MISSED DOSE: If you miss a dose, take the missed dose as soon as you remember. Do not take the missed dose if it is within 6 hours of your next dose. In that case, skip the missed dose and resume your usual dosing schedule. It is important not to miss doses of this drug.

STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854- 1166 (USA) or 1-800-668-1507 (Canada).

Information last revised March 2011 Copyright(c) 2011 First DataBank, Inc.