Reye's Syndrome
David Perlstein, MD, MBA, FAAP
Dr. Perlstein received his Medical Degree from the University of Cincinnati and then completed his internship and residency in pediatrics at The New York Hospital, Cornell medical Center in New York City. After serving an additional year as Chief Pediatric Resident, he worked as a private practitioner and then was appointed Director of Ambulatory Pediatrics at St. Barnabas Hospital in the Bronx.
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
- Reye's syndrome facts
- What is Reye's syndrome?
- What causes Reye's syndrome?
- What are risk factors for Reye's syndrome?
- What are Reye's syndrome symptoms and signs?
- How is Reye's syndrome diagnosed?
- What is the treatment for Reye's syndrome?
- What is the prognosis for Reye's syndrome?
- Can Reye's syndrome be prevented?
- What research is being done on Reye's syndrome?
- Where can I find more information about Reye's syndrome?
Reye's syndrome facts
- Reye's syndrome is a rare and severe illness affecting children.
- Reye's syndrome is associated with viral infection and aspirin use.
- Patients with Reye's syndrome present with vomiting and mental-status changes.
- Diagnosing Reye's syndrome primarily depends on the clinical history of symptoms.
- The most common abnormal laboratory tests with Reye's syndrome include elevated liver enzymes, elevated ammonia levels, and low serum glucose levels.
- Treatment is supportive, and even with treatment severe cases result in permanent brain damage and death.
- Since educating parents about the dangers of aspirin use, the incidence of Reye's syndrome has decreased markedly.
What is Reye's syndrome?
Reye's syndrome is a rare but often severe and even fatal illness that primarily occurs in children and adolescents. Children diagnosed with Reye's syndrome generally present with vomiting and mental-status changes. The illness can resolve spontaneously or progress to coma and death. Although the cause is still unclear, studies have identified that there is a relationship between some viral infections and the use of aspirin medications. The CDC recommended educating parents about the dangers of treating children with aspirin in the 1980s, and now the disease occurs very rarely. The syndrome was initially described in 1963 by Dr. Ralph Douglas Reye.
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