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Reye Syndrome (cont.)

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What is the prognosis for Reye's syndrome?

There is significant variation in outlook amongst children diagnosed with Reye's syndrome. It is dependent upon the severity and progression of the disease. Some children may have mild disease and completely recover, and others may develop permanent dysfunction of the brain or die from the disease. In general, children who are diagnosed and treated early in the course of the illness have a better outcomes. Studies also suggest that those presenting with high ammonia levels have a worse prognosis.

Can Reye's syndrome be prevented?

Although we do not know how to completely prevent Reye's syndrome, we do know that reducing aspirin use in children has resulted in a decrease in the incidence of the illness. In 1980, there were over 500 cases of Reye's syndrome in the United States, and now there are only one to two cases per year. Similar statistics have been seen in the United Kingdom as well.

What research is being done on Reye's syndrome?

Most research that is being done focuses on understanding what the triggers are for Reye's syndrome and how aspirin is involved in the disease. In addition, some are trying to determine why some patients progress rapidly and some cases simply resolve.

Where can I find more information about Reye's syndrome?

National Reye Syndrome Foundation
http://www.reyessyndrome.org

REFERENCES:

Glasgow, J.F. and B. Middleton. "Reye's Syndrome -- Insights on Causation and Prognosis." Arch Dis Child 85.5 (2001): 351-353.

Pugliese, A., T. Beltramo, and D. Torre. "Reye's and Reye's-like Syndromes." Cell Biochem Function 26 (2008): 741-746.


Last Editorial Review: 10/20/2011


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Reye's Syndrome - Experience and Concerns Question: Do you avoid taking aspirin and giving it to your children for fear of developing Reye's syndrome? Please share your concerns.
Reye's Syndrome - Signs and Symptoms Question: Have you or your child ever had symptoms similar to Reye's syndrome? What was the diagnosis?
Reye's Syndrome - What Happens? Question: Have you ever known anyone with Reye's syndrome? If so, what was the progression of the illness?
Source: MedicineNet.com
http://www.medicinenet.com/reye_syndrome/article.htm

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