August 24, 2016
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" Type 2 diabetes usually begins with insulin resistance, a condition in which the body produces insulin but isn't able to use it effectively. As a result, glucose builds up in blood and may ultimately damage nerves, blood vessels, and other b"...



Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)


Rezulin (troglitazone (removed from the us market 3/21/00)) should be taken with meals. If the dose is missed at the usual meal, it may be taken at the next meal. If the dose is missed on one day, the dose should not be doubled the following day.

It is important to adhere to dietary instructions and to regularly have blood glucose and glycosylated hemoglobin tested. During periods of stress such as fever, trauma, glucose and glycosyin jection, or surgery, insulin requirements may change and patients should seek the advice of their physician. Patients who develop nausea, vomiting, abdominal pain. fatigue, anorexia, dark urine or other symptoms suggestive of hepatic dysfunction or jaundice should immediately report these signs or symptoms to their physician.

When using combination therapy with insulin or oral hypoglycemic agents. the risks of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be explained to patients and their family members.

Use of Rezulin (troglitazone (removed from the us market 3/21/00)) can cause resumption of ovulation in women taking oral contraceptives and in patients with polycystic ovary disease. Therefore, a higher dose of an oral contraceptive or an alternative method of contraception should be considered.

Rezulin (troglitazone (removed from the us market 3/21/00)) may affect other medications used in diabetic patients. Patients started on Rezulin (troglitazone (removed from the us market 3/21/00)) should ask their physician to review their other medications to make sure that they are not affected by Rezulin.


Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

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