font size

Rheumatoid Factor (cont.)

Medical Author:

Can rheumatoid factor be present in a patient without rheumatoid arthritis?

Yes. Rheumatoid factor is also present in patients with other conditions, including other connective tissue diseases (such as systemic lupus erythematosus), some infectious diseases (such as infectious hepatitis, syphilis, infectious mononucleosis, parasites, and tuberculosis), liver disease, and sarcoidosis. Rheumatoid factor can also sometimes be present in normal individuals without diseases. This occurs more frequently in people with family members who have rheumatoid arthritis.

What significance does the rheumatoid factor hold for patients with rheumatoid arthritis?

High levels of rheumatoid factor are associated with more severe rheumatoid disease. This factor is also associated with a higher tendency to develop non-joint manifestations of rheumatoid disease, such as rheumatoid nodules and rheumatoid lung disease.

Medically reviewed by Kirkwood Johnston, MD; American Board of Internal Medicine with subspecialty in Rheumatology

REFERENCE:

Klippel, J.H., et al. Primer on the Rheumatic Diseases. New York: Springer, 2008.


Medically Reviewed by a Doctor on 2/21/2014

Patient Comments

Viewers share their comments

Rheumatoid Factor - Testing Question: Did you test positive for rheumatoid factor? How did your treatment progress?
Source: MedicineNet.com
http://www.medicinenet.com/rheumatoid_factor/article.htm

Arthritis

Get the latest treatment options

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations