"Rheumatoid arthritis overview
Rheumatoid arthritis (RA) is a disease in which the body's immune system attacks its own joints. This results in pain, swelling and potentially permanent damage. About 1.5 million people in the United State"...
Patients should be informed of the early signs and symptoms of toxicity, of the need to see their physician promptly if they occur, and the need for close follow-up, including periodic laboratory tests to monitor toxicity.
Both the physician and pharmacist should emphasize to the patient that the recommended dose is taken weekly in rheumatoid arthritis and psoriasis, and that mistaken daily use of the recommended dose has led to fatal toxicity. Patients should be encouraged to read the Patient Instructions sheet within the Dose Pack. Prescriptions should not be written or refilled on a PRN basis.
Patients should be informed of the potential benefit and risk in the use of methotrexate. The risk of effects on reproduction should be discussed with both male and female patients taking methotrexate.
Last reviewed on RxList: 8/29/2013
This monograph has been modified to include the generic and brand name in many instances.
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