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RHINOCORT AQUA 32 mcg
(budesonide) Nasal Spray
- Patient Information:
Details with Side Effects
Budesonide, the active ingredient of RHINOCORT AQUA (budesonide) Nasal Spray, is an anti-inflammatory synthetic corticosteroid.
It is designated chemically as (RS)-11-beta, 16-alpha, 17, 21-tetrahydroxypregna-l,4-diene-3,20-dione cyclic 16, 17-acetal with butyraldehyde.
Budesonide is provided as the mixture of two epimers (22R and 22S).
The empirical formula of budesonide is C25H34O6 and its molecular weight is 430.5.
Its structural formula is:
Budesonide is a white to off-white, odorless powder that is practically insoluble in water and in heptane, sparingly soluble in ethanol, and freely soluble in chloroform.
Its partition coefficient between octanol and water at pH 5 is 1.6 x103.
RHINOCORT AQUA (budesonide) Nasal Spray is an unscented, metered-dose, manual-pump spray formulation containing a micronized suspension of budesonide in an aqueous medium. Microcrystalline cellulose and carboxymethyl cellulose sodium, dextrose anhydrous, polysorbate 80, disodium edetate, potassium sorbate, and purified water are contained in this medium; hydrochloric acid is added to adjust the pH to a target of 4.5.
RHINOCORT AQUA Nasal Spray delivers 32 mcg of budesonide per spray.
Each bottle of RHINOCORT AQUA (budesonide) Nasal Spray 32 mcg contains 120 metered sprays after initial priming.
Prior to initial use, the container must be shaken gently and the pump must be primed by actuating eight times. If used daily, the pump does not need to be reprimed. If not used for two consecutive days, reprime with one spray or until a fine spray appears. If not used for more than 14 days, rinse the applicator and reprime with two sprays or until a fine spray appears.
What are the possible side effects of budesonide nasal (Rhinocort Aqua)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- severe or ongoing nose bleed;
- sores in the nose that won't heal;
- wheezing, trouble breathing;
- vision problems; or
- fever, chills, body aches, flu symptoms.
Less serious side effects may include:
- dry or sore throat, cough;
- irritation in your nose;
What are the precautions when taking budesonide (Rhinocort Aqua)?
Before using nasal budesonide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (such as glaucoma, cataracts), infections (including tuberculosis), recent nose problems (such as injury, ulcers, surgery).
Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
Rarely, using corticosteroid medications for a long time can make it more difficult...
Last reviewed on RxList: 2/24/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Rhinocort Aqua Information
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