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- Clinician Information:
Rhogam Patient Information including How Should I Take
In this Article
- What is RHo (D) immune globulin (Rhogam)?
- What are the possible side effects of RHo (D) immune globulin?
- What is the most important information I should know about RHo (D) immune globulin?
- What should I discuss with my healthcare provider before I receive RHo (D) immune globulin?
- How is RHo (D) immune globulin given?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while receiving RHo (D) immune globulin?
- What other drugs will affect RHo (D) immune globulin?
- Where can I get more information?
What should I discuss with my healthcare provider before I receive RHo (D) immune globulin?
You should not receive this medication if you have ever had an allergic reaction to an immune globulin or if you have immune globulin A (IgA) deficiency with antibody to IgA. You should not receive RHo (D) immune globulin if you have hemolytic anemia (a lack of red blood cells).
To make sure you can safely receive RHo (D) immune globulin, tell your doctor if you have any of these other conditions:
- heart disease or a history of coronary artery disease (hardened arteries);
- high triglycerides (a type of fat in the blood);
- a bleeding disorder (such as hemophilia); or
- immune globulin A (IgA) deficiency.
RHo (D) immune globulin is used during and after pregnancy. This medication is not known to be harmful to a baby during pregnancy or while breast-feeding.
If you are receiving this medication to treat a mismatched blood transfusion, tell your doctor if you are pregnant or if you ever plan to become pregnant.
If you are an Rh-negative woman and you become pregnant, you must tell your doctor if you have ever been exposed to Rh-positive blood in your lifetime. This includes exposure from a mismatched blood transfusion, or exposure during your first pregnancy. Your history of exposure and treatment will be extremely important to each and every one of your pregnancies.
RHo (D) immune globulin is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How is RHo (D) immune globulin given?
RHo (D) immune globulin is injected into a muscle or a vein. You will receive this injection in a clinic or hospital setting.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely for at least 8 hours after you receive immune globulin. Your urine will also need to be tested every 2 to 4 hours.
For treatment during pregnancy, this medication is usually given at regular intervals during the last half of the pregnancy, and again after the baby is born.
For treatment of a mismatched blood transfusion, the medication is given when symptoms of an immune response appear (when the body starts making Rh antibodies).
To be sure this medicine is helping your condition, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.
This medication can cause false results with certain lab tests for glucose (sugar) in the blood. Tell any doctor who treats you that you are using RHo (D) immune globulin.
Additional Rhogam Information
- Rhogam Drug Interactions Center: rho(d) immune globulin im
- Rhogam Side Effects Center
- Rhogam FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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