November 24, 2015
Recommended Topic Related To:


"Researchers have created a genetically engineered mouse that allows them to observe the movement of molecules in the brain that may be involved in the formation of memories. The transgenic mouse carries a fluorescently labeled messenger RNA (mRNA"...




No specific antidote or information on treatment of overdosage with RILUTEK (riluzole) is available. In the event of overdose, RILUTEK (riluzole) therapy should be discontinued immediately. Experience with riluzole overdose in humans is limited. Neurological and psychiatric symptoms, acute toxic encephalopathy with stupor, coma, and methemoglobinemia have been observed in isolated cases. Treatment should be supportive and directed toward alleviating symptoms.

Severe methemoglobinemia may be rapidly reversible after treatment with methylene blue. The estimated oral median lethal dose is 94 mg/kg and 39 mg/kg for male mice and rats, respectively.


RILUTEK (riluzole) is contraindicated in patients who have a history of severe hypersensitivity reactions to riluzole or any of the tablet components.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 8/4/2009


Rilutek - User Reviews

Rilutek User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Rilutek sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

WebMD Daily

Get breaking medical news.