Ritalin LA (Methylphenidate Hydrochloride Extended-Release Capsules) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Ritalin LA

Adult ADHD (Attention Deficit Hyperactivity Disorder) »

What Is Attention Deficit Hyperactivity Disorder (ADHD)?

Attention deficit hyperactivity disorder (ADHD) is one of the most well-recognized childhood developmental problems. This condition is characterized by inattention, hyperactivity and impulsiveness. It is now known that these symptoms continue into adulthood for about 60% of children with ADHD. That translates into 4% of the US adult population, or 8 million adults. However, few adults are identified or treated for adult ADHD.

ADHD in Adults

Adults with ADHD may have difficulty following directions, remembering information, concentrating, organizing tasks or completing work within time limits. If these difficulties are not managed appropriately, they can cause associated behavioral, emotional, social, vocational and academic problems.

Adult ADHD Stats

ADHD afflicts approximately 3% to 5% of school-age children and an es...

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Ritalin LA

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Ritalin LA®
(methylphenidate hydrochloride) Extended-Release Capsules

DRUG DESCRIPTION

Methylphenidate hydrochloride is a central nervous system (CNS) stimulant.

Ritalin LA® (methylphenidate hydrochloride) extended-release capsules is an extended-release formulation of methylphenidate with a bi-modal release profile. Ritalin LA® (methylphenidate hydrochloride extended-release capsules) uses the proprietary SODAS® (Spheroidal Oral Drug Absorption System) technology. Each bead-filled Ritalin LA (methylphenidate hydrochloride extended-release capsules) capsule contains half the dose as immediate-release beads and half as enteric-coated, delayed-release beads, thus providing an immediate release of methylphenidate and a second delayed release of methylphenidate. Ritalin LA (methylphenidate hydrochloride extended-release capsules) 10, 20, 30, and 40 mg capsules provide in a single dose the same amount of methylphenidate as dosages of 5, 10, 15, or 20 mg of Ritalin® tablets given b.i.d.

The active substance in Ritalin LA (methylphenidate hydrochloride extended-release capsules) is methyl α-phenyl-2-piperidineacetate hydrochloride, and its structural formula is

Ritalin LA®
(methylphenidate hydrochloride) Structural Formula Illustration

Methylphenidate hydrochloride USP is a white, odorless, fine crystalline powder. Its solutions are acid to litmus. It is freely soluble in water and in methanol, soluble in alcohol, and slightly soluble in chloroform and in acetone. Its molecular weight is 269.77.

Inactive ingredients: ammonio methacrylate copolymer, black iron oxide (10 and 40 mg capsules only), gelatin, methacrylic acid copolymer, polyethylene glycol, red iron oxide (10 and 40 mg capsules only), sugar spheres, talc, titanium dioxide, triethyl citrate, and yellow iron oxide (10, 30, and 40 mg capsules only).

What are the possible side effects of methylphenidate?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking methylphenidate and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeats;
feeling like you might pass out;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
aggression, restlessness, hallucinations, unusual behavior, or motor tics...

Read All Potential Side Effects and See Pictures of Ritalin LA »

What are the precautions when taking methylphenidate hydrochloride extended-release capsules (Ritalin LA)?

Before taking methylphenidate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain mental/mood conditions (e.g., agitation, psychosis), heart/blood vessel disease (e.g., irregular heartbeat/rhythm, coronary artery disease, angina, heart failure, cardiomyopathy), problems with heart structure (e.g., valve problems), history of heart attack or stroke, severe anxiety/tension, glaucoma, motor tics.

Before using this medication, tell your...

Read All Potential Precautions of Ritalin LA »

Last reviewed on RxList: 5/21/2012
This monograph has been modified to include the generic and brand name in many instances.