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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Robaxisal Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 2/7/2016

Robaxisal (methocarbamol and aspirin) is a combination of a muscle relaxant and a type of pain reliever called a salicylate, used together, along with rest and physical therapy, to treat injuries and other painful muscular conditions. The brand name Robaxisal is discontinued, but generic versions may be available. Common side effects of Robaxisal (methocarbamol and aspirin) include drowsiness, dizziness, lightheadedness, fainting, stomach upset, nausea, vomiting, diarrhea, metallic taste in the mouth, heartburn, blurred vision, headache, ringing in the ears, or colored urine (brown, black, or green color - this is not harmful).

The dose of Robaxisal for adults and children over 12 years of age is two tablets four times daily. Robaxisal may interact with antidepressants, alcohol, antihistamines, sedatives, other pain relievers, anxiety medicines, other muscle relaxants, anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs), or other salicylates. Tell your doctor all medications and supplements you use. Aspirin is not recommended for use during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor. Do not use Robaxisal during the last 3 months of pregnancy because of possible harm to the fetus or problems during delivery. It is unknown if methocarbamol passes into breast milk. Aspirin passes into breast milk and may have undesirable effects on a nursing infant. Breastfeeding while using this drug is not recommended.

Our Robaxisal (methocarbamol and aspirin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Robaxisal Overview - Patient Information: Side Effects

SIDE EFFECTS: Drowsiness, dizziness, lightheadedness, stomach upset, nausea/vomiting, heartburn, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, dark urine, yellowing eyes/skin, persistent nausea/vomiting, hearing problems (such as ringing in the ears, hearing loss), change in the amount of urine, fast/pounding heartbeat, unusual tiredness, fainting, mental/mood changes (such as confusion, forgetfulness).

This drug may infrequently cause serious (rarely fatal) bleeding from the stomach or intestines. If you notice any of the following unlikely but serious side effects, stop taking this medication and consult your doctor or pharmacist immediately: black stool, vomit that looks like coffee grounds, persistent stomach/abdominal pain.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Robaxisal (Methocarbamol and Aspirin)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Robaxisal FDA Prescribing Information: Side Effects
(Adverse Reactions)


The most frequent adverse reaction to methocarbamol is dizziness or lightheadedness and nausea. This occurs in about one in 20-25 patients. Less frequent reactions are drowsiness, blurred vision, headache, fever, allergic manifestations such as urticaria, pruritus, and rash.

Adverse reactions that have been associated with the use of aspirin include: nausea and other gastrointestinal discomfort, gastritis, gastric erosion, vomiting, constipation, diarrhea, angio-edema, asthma, rash, pruritus, urticaria.

Gastrointestinal discomfort may be minimized by taking Robaxisal (methocarbamol and aspirin) with food.

Read the entire FDA prescribing information for Robaxisal (Methocarbamol and Aspirin)

Robaxisal - User Reviews

Robaxisal User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Robaxisal sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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