"The US Food and Drug Administration (FDA) has okayed expanded use of the combination antiviral drug ledipasvir/sofosbuvir (Harvoni, Gilead Sciences) in patients with genotype 4, 5, and 6 chronic hepatitis C virus (HCV) infection and in p"...
Roferon-A (interferon alfa-2a, recombinant) is contraindicated in patients with:
- Hypersensitivity to Roferon-A (interferon alfa-2a, recombinant) or any of its components
- Autoimmune hepatitis
- Hepatic decompensation (Child-Pugh class B and C) before or during treatment
Roferon-A (interferon alfa-2a, recombinant) is contraindicated in neonates and infants because it contains benzyl alcohol. Benzyl alcohol is associated with an increased incidence of neurologic and other complications in neonates and infants, which are sometimes fatal.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 11/11/2008
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