In this Article

• What is flumazenil (Romazicon)?
• What are the possible side effects of flumazenil (Romazicon)?
• What is the most important information I should know about flumazenil (Romazicon)?
• What should I discuss with my health care provider before receiving flumazenil (Romazicon)?
• How is flumazenil given (Romazicon)?
• What happens if I miss a dose (Romazicon)?
• What happens if I overdose (Romazicon)?
• What should I avoid while receiving flumazenil (Romazicon)?
• What other drugs will affect flumazenil (Romazicon)?
• Where can I get more information?

What happens if I miss a dose (Romazicon)?

Since this medication is given as needed by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose (Romazicon)?

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include feeling anxious or agitated, muscle tightness, or seizure (convulsions).

What should I avoid while receiving flumazenil (Romazicon)?

Flumazenil can cause side effects that may impair your thinking or reactions. For at least 18 hours after you leave the hospital or surgery center, do not drive or do anything else that requires you to be awake and alert. Continue to limit these activities until you no longer feel sedated (weak, drowsy, or dizzy).

Even though you may feel alert after waking up from sedation, your judgment or reactions may still be impaired. Follow your caregivers' instructions about limiting activities after receiving flumazenil.

Do not drink alcohol for at least 18 hours after receiving flumazenil, or if you still feel sedated.

What other drugs will affect flumazenil (Romazicon)?

Before receiving flumazenil, tell your doctor if you have recently drank an alcoholic beverage, or if you are using any of the following drugs:

• seizure medication;
• eszopiclone (Lunesta);
• antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil); or
• diazepam (Valium) or similar medicines such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), estazolam (ProSom), flurazepam (Dalmane), lorazepam (Ativan), midazolam (Versed), temazepam (Restoril), triazolam (Halcion), and others.

If you are using any of these drugs, you may not be able to use flumazenil, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect flumazenil. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist has information about flumazenil written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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