"NEW YORK (Reuters Health) - Triple therapy combining a proton-pump inhibitor (PPI), amoxicillin, and high-dose metronidazole (PAM) given thrice daily for 14 days provides Helicobacter pylori eradication rates similar to those with triple-therapy "...
(mesalamine) Rectal Suspension Enema 4.0 grams/unit (60 mL)
The active ingredient in ROWASA® (mesalamine) Rectal Suspension Enema, a disposable (60 mL) unit, is mesalamine, also known as 5-aminosalicylic acid (5-ASA). Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid.
The empirical formula is C7H7N03, representing a molecular weight of 153.14. The structural formula is:
Each rectal suspension enema unit contains 4 grams of mesalamine. In addition to mesalamine the preparation contains the inactive ingredients carbomer934P, edetate disodium, potassium acetate, potassium metabisulfite, purified water and xanthan gum. Sodium benzoate is added as a preservative. The disposable unit consists of an applicator tip protected by a polyethylene cover and lubricated with USP white petrolatum. The unit has a one-way valve to prevent back flow of the dispensed product.
What are the possible side effects of mesalamine rectal (Canasa, Canasa Pac, Rowasa)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using mesalamine rectal and call your doctor at once if you have severe stomach pain, cramping, fever, headache, and bloody diarrhea.
Less serious side effects may include:
- mild nausea, vomiting, stomach cramps, diarrhea, gas;
- fever, sore throat, or other flu symptoms;
- rectal pain, constipation;
- headache or dizziness;
- tired feeling;...
What are the precautions when taking mesalamine rectal suspension enema (Rowasa)?
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to other medications that are broken down into mesalamine (such as balsalazide, sulfasalazine, olsalazine); or to other salicylates (such as aspirin); or if you have any other allergies. This product may contain inactive ingredients (such as sulfites), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, kidney problems, pancreas problems (pancreatitis), inflammation of the sac around the heart (pericarditis).
This medication is similar to aspirin. Children and teenagers should not take aspirin or aspirin-related medications (such as...
Last reviewed on RxList: 2/24/2017
This monograph has been modified to include the generic and brand name in many instances.
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