Brand Names: Rythmol, Rythmol SR

Generic Name: propafenone (Pronunciation: proe PAF e none)

• What is propafenone (Rythmol)?
• What are the possible side effects of propafenone (Rythmol)?
• What is the most important information I should know about propafenone (Rythmol)?
• What should I discuss with my healthcare provider before taking propafenone (Rythmol)?
• How should I take propafenone (Rythmol)?
• What happens if I miss a dose (Rythmol)?
• What happens if I overdose (Rythmol)?
• What should I avoid while taking propafenone (Rythmol)?
• What other drugs will affect propafenone (Rythmol)?
• Where can I get more information?

What is propafenone (Rythmol)?

Propafenone is in a group of drugs called Class IC anti-arrhythmics. It affects the way your heart beats.

Propafenone is used in certain situations to prevent serious heart rhythm disorders.

Propafenone may also be used for other purposes not listed in this medication guide.

Proprafenone 150 mg-ETH

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Proprafenone 225 mg-ETH

round, white, imprinted with 332, ETH

Proprafenone 300 mg-ETH

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Rhythmol SR 225 mg

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Rythmol 150 mg

round, white, imprinted with 150 LOGO

Rythmol 225 mg

round, white, imprinted with 225 LOGO

What are the possible side effects of propafenone (Rythmol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• feeling short of breath, even with mild exertion;
• swelling, rapid weight gain;
• slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);
• pale skin, easy bruising or bleeding, unusual weakness;
• confusion, unusual thoughts or behavior; or
• seizure.

Less serious side effects may include:

• dizziness;
• unusual or unpleasant taste in your mouth;
• nausea, vomiting;
• warmth, redness, or tingly feeling under your skin;
• constipation;
• headache;
• tired feeling;
• ringing in your ears;
• unusual dreams; or
• blurred vision.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about propafenone (Rythmol)?

You should not use this medication if you are allergic to propafenone, or if you have untreated or uncontrolled congestive heart failure, a heart condition called "sick sinus syndrome" or "AV block" (unless you have a pacemaker), slow heartbeats or severely low blood pressure, an electrolyte imbalance, or a breathing disorder such as asthma.

Before you take propafenone, tell your doctor if you have congestive heart failure, liver or kidney disease, lupus, arthritis, myasthenia gravis, or if you have had a heart attack within the past 2 years.

You will need to receive your first few doses of propafenone in a hospital setting in case the medication causes serious side effects. Your heart rate will be constantly monitored using an electrocardiograph or ECG (sometimes called an EKG). This machine measures electrical activity of the heart.

Call your doctor at once if you have a serious side effect such as weak pulse, slow breathing, feeling like you might pass out, feeling short of breath, swelling, rapid weight gain, pale skin, easy bruising or bleeding, unusual weakness, confusion, unusual thoughts or behavior, or seizure.