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In this Article

• What is propafenone (Rythmol SR)?
• What are the possible side effects of propafenone (Rythmol SR)?
• What is the most important information I should know about propafenone (Rythmol SR)?
• What should I discuss with my healthcare provider before taking propafenone (Rythmol SR)?
• How should I take propafenone (Rythmol SR)?
• What happens if I miss a dose (Rythmol SR)?
• What happens if I overdose (Rythmol SR)?
• What should I avoid while taking propafenone (Rythmol SR)?
• What other drugs will affect propafenone (Rythmol SR)?
• Where can I get more information?

What happens if I miss a dose (Rythmol SR)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Rythmol SR)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include drowsiness, slow heart rate, feeling like you might pass out, or seizure (convulsions).

What should I avoid while taking propafenone (Rythmol SR)?

Grapefruit and grapefruit juice may increase your blood levels of propafenone which could lead to unwanted side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What other drugs will affect propafenone (Rythmol SR)?

Many drugs can interact with propafenone. Below is just a partial list. Tell your doctor if you are using:

• cimetidine (Tagamet),
• digoxin (digitalis, Lanoxin);
• ketoconazole (Nizoral);
• orlistat (alli, Xenical);
• quinidine (Quinaglute, Quinidex, Quin-Release);
• rifampin (Rifadin, Rifamate, Rimactane);
• a blood thinner such as warfarin (Coumadin);
• an antidepressant such as desipramine (Norpramin), fluoxetine (Prozac), imipramine (Tofranil), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor);
• HIV or AIDS medication such as ritonavir (Norvir) or saquinavir (Invirase);
• another heart rhythm medication such as amiodarone (Cordarone, Pacerone);
• medicine to treat psychiatric disorders, such as haloperidol (Haldol); or
• a beta-blocker such as atenolol (Tenormin), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others.

This list is not complete and there may be other drugs that can interact with propafenone. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about propafenone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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