In this Article
- What other names is Saffron known by?
- What is Saffron?
- How does Saffron work?
- Are there safety concerns?
- Dosing considerations for Saffron.
Ingesting large amounts of saffron can cause poisoning including yellow appearance of the skin, eyes, and mucous membranes; vomiting; dizziness; bloody diarrhea; bleeding from the nose, lips, and eyelids; numbness; and other serious side effects.
Do not take saffron if:
- You are pregnant or breast-feeding.
- You are allergic to related plants such as Lolium, Olea, or Salsola.
- You have bipolar disorder.
- For depression: 30 mg/day of a specific saffron extract (Novin Zaferan Co, Iran). A different saffron extract 15 mg twice daily has also been used.
- For premenstrual syndrome (PMS): 15 mg of a specific ethanol saffron extract twice daily (Department of Cultivation and Development of Institute of Medicinal Plants, Tehran, Iran).
- For menstrual discomfort: 500 mg of a specific combination product containing saffron, celery seed and anise extracts (SCA, Gol Daro Herbal Medicine Laboratory) taken three times a day for the first three days of menstruation.
- For Alzheimer's disease: 30 mg/day of a specific saffron product (IMPIRAN, Iran).
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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