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Samsca Patient Information including If I Miss a Dose
In this Article
- What is tolvaptan (Samsca)?
- What are the possible side effects of tolvaptan (Samsca)?
- What is the most important information I should know about tolvaptan (Samsca)?
- What should I discuss with my health care provider before taking tolvaptan (Samsca)?
- How should I take tolvaptan (Samsca)?
- What happens if I miss a dose (Samsca)?
- What happens if I overdose (Samsca)?
- What should I avoid while taking tolvaptan (Samsca)?
- What other drugs will affect tolvaptan (Samsca)?
- Where can I get more information?
What happens if I miss a dose (Samsca)?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Samsca)?
Seek emergency medical attention if you think you have used too much of this medicine. Overdose can cause dehydration (weakness, extreme thirst, increased urination, decreased sweating, hot or dry skin).
What should I avoid while taking tolvaptan (Samsca)?
Grapefruit and grapefruit juice may interact with tolvaptan and lead to potentially dangerous effects. Avoid drinking grapefruit juice while taking tolvaptan.
What other drugs will affect tolvaptan (Samsca)?
Many drugs can interact with tolvaptan. Below is just a partial list. Tell your doctor if you are using:
- aprepitant (Emend);
- birth control pills;
- cyclosporine (Gengraf, Neoral, Sandimmune);
- digoxin (digitalis, Lanoxin);
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- St. John's wort;
- an antibiotic such as doxycycline (Adoxa, Doryx, Oracea, Vibramycin), metronidazole (Flagyl), norfloxacin (Noroxin), tetracycline (Ala-Tet, Brodspec, Sumycin),
- an antidepressant such as desipramine (Norpramin) or sertraline (Zoloft);
- a barbiturate such as phenobarbital (Solfoton) and others;
- a diuretic (water pill) such as amiloride (Midamor), spironolactone (Aldactone, Aldactazide), triamterene (Dyrenium, Dyazide, Maxzide);
- heart or blood pressure medication such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), and others;
- HIV or AIDS medicine such as efavirenz (Sustiva), etravirine (Intelence), nevirapine (Viramune), and others;
- potassium supplements, potassium citrate (K-Lyte, Urocit-K, Citrolith, Polycitra), and others; or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin), and others.
Where can I get more information?
Your pharmacist can provide more information about tolvaptan.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Samsca Information
- Samsca Drug Interactions Center: tolvaptan oral
- Samsca Side Effects Center
- Samsca Overview including Precautions
- Samsca FDA Approved Prescribing Information including Dosage
Samsca - User Reviews
Samsca User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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