Sanctura (Trospium) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 21, 2012

Sanctura

Urinary Incontinence in Children »

Urinary incontinence in children facts

Urinary incontinence in children is very common.
Nighttime wetting (nocturnal enuresis) is more common than daytime wetting (diurnal enuresis).
Most urinary incontinence is nonorganic and resolves without intervention.
Persistent primary enuresis and secondary enuresis may require further medical evaluation.
Treatment for most cases of enuresis involves behavioral modification.
Bedwetting alarms are very effective.
Medications should be reserved for select children.
Less than 1% of all affected children have persistent incontinence into adulthood.

What is urinary incontinence?

Very simply stated, urinary incontinence is defined as the loss of complete control of the act of urination or the involuntary emptying of the bladder. It is also referred to as enuresis. It can be caused by any number of factors,...

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SANCTURA®
(trospium chloride) 20 mg Tablets

DRUG DESCRIPTION

SANCTURA® (trospium chloride) is a quaternary ammonium compound with the chemical name of Spiro[8azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (1α, 3β, 5α). The empirical formula of trospium chloride is C₂₅H₃₀ClNO₃ and its molecular weight is 427.97. The structural formula of trospium chloride is represented below:

SANCTURA® (trospium chloride) Structural Formula Illustration

Trospium chloride is a fine, colorless to slightly yellow, crystalline solid. The compound's solubility in water is approximately 1 g/2 mL.

Each SANCTURA® tablet contains 20 mg of trospium chloride and is to be given orally. Each tablet also contains the following inactive ingredients: sucrose, wheat starch, microcrystalline cellulose, talc, lactose monohydrate, calcium carbonate, titanium dioxide, stearic acid, croscarmellose sodium, povidone, polyethylene glycol 8000, colloidal silicon dioxide, ferric oxide, carboxymethylcellulose sodium, white wax, magnesium stearate, and carnauba wax.

What are the possible side effects of trospium (Sanctura, Sanctura XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using trospium and call your doctor at once if you urinate less than usual or not at all.

Less serious side effects may include:

dry mouth or throat;
dry eyes, blurred vision;
constipation;
stomach pain, bloating, gas;
drowsiness, or
mild skin rash.

This is not a...

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What are the precautions when taking trospium (Sanctura)?

Before taking trospium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain type of glaucoma (uncontrolled narrow-angle type), inability to urinate (urinary retention), delayed or slow emptying of your stomach.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, constipation, other stomach conditions (such as ulcerative colitis, intestinal atony), myasthenia...

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Last reviewed on RxList: 9/30/2011
This monograph has been modified to include the generic and brand name in many instances.