May 27, 2017
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Overdosage with antimuscarinic agents, including SANCTURA®, can result in severe antimuscarinic effects. Supportive treatment should be provided according to symptoms. In the event of overdosage, electrocardiographic monitoring is recommended.

A 7-month-old baby experienced tachycardia and mydriasis after administration of a single dose of trospium 10 mg given by a sibling. The baby's weight was reported as 5 kg. Following admission into the hospital and about 1 hour after ingestion of the trospium, medicinal charcoal was administered for detoxification. While hospitalized, the baby experienced mydriasis and tachycardia up to 230 beats per minute. Therapeutic intervention was not deemed necessary. The baby was discharged as completely recovered the following day.


SANCTURA® is contraindicated in patients with:

  • urinary retention
  • gastric retention
  • uncontrolled narrow-angle glaucoma.
  • known hypersensitivity to the drug or its ingredients. Angioedema, rash and anaphylactic reaction have been reported.
This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 2/14/2017


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