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(trospium chloride) Extended Release Capsules
SANCTURA XR® is an extended-release formulation of trospium chloride, a quaternary ammonium compound with the chemical name of Spiro [8-azoniabicyclo[3.2.1]octane-8,r-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (lα, 3β, 5α). The empirical formula of trospium chloride is C25H30ClNO3 and its molecular weight is 427.97. The structural formula of trospium chloride is represented below:
Trospium chloride is a fine, colorless to slightly yellow, crystalline solid. The compound's solubility in water is approximately 1 g/2 mL.
SANCTURA XR® capsules contain 60 mg of trospium chloride, a muscarinic antagonist, for oral administration. Each capsule also contains the following inactive ingredients: sugar spheres, methacrylic acid copolymer, ethyl cellulose, hydroxypropyl methylcellulose, triethyl citrate, talc, and Opadry® white.
What are the possible side effects of trospium (Sanctura, Sanctura XR)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using trospium and call your doctor at once if you have a serious side effect such as:
- severe stomach pain or bloating;
- severe constipation;
- urinating less than usual or not at all; or
- confusion, hallucinations.
Less serious side effects may include:
- dry mouth or throat;
- mild constipation;
- upset stomach,...
What are the precautions when taking trospium chloride extended release capsule (Sanctura XR)?
Before taking trospium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain type of glaucoma (uncontrolled narrow-angle type), inability to urinate (urinary retention), delayed or slow emptying of your stomach.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, constipation, other stomach conditions (such as ulcerative colitis, intestinal atony), myasthenia...
Last reviewed on RxList: 9/27/2012
This monograph has been modified to include the generic and brand name in many instances.
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