Sanctura XR (Trospium Chloride Extended Release Capsule) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 27, 2012

Sanctura XR

Urinary Incontinence »

Urinary incontinence (UI) in men facts

*Urinary incontinence (UI) in men facts Medically Edited by: Melissa Conrad Stöppler, MD

The definition of urinary incontinence in men is the unintentional loss of urine. Weak bladder muscles, overactive bladder muscles, certain prostate conditions, and nerve damage are just some of the possible underlying causes of urinary incontinence in men.
There are different types of urinary incontinence in men, including stress incontinence, urge incontinence, and overflow incontinence.
Diagnosis of urinary incontinence in men may involve a physical exam, an ultrasound, urodynamic testing, and tests including an electroencephalogram (EEG) and an electromyogram (EMG). The doctor will also take a medical history and may recommend keeping a bladder diary.
Treatment of urinary incontinence in men may include behavioral treatments, like bladder training and Kegel exercises, medication, surgery, or...

Read the Urinary Incontinence article »

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Sanctura XR

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SANCTURA XR®
(trospium chloride) Extended Release Capsules

DRUG DESCRIPTION

SANCTURA XR® is an extended-release formulation of trospium chloride, a quaternary ammonium compound with the chemical name of Spiro [8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], 3-[(hydroxydiphenylacetyl)oxy]-, chloride, (lα, 3β, 5α). The empirical formula of trospium chloride is C₂₅H₃₀ClNO₃ and its molecular weight is 427.97. The structural formula of trospium chloride is represented below:

SANCTURA XR®
(trospium chloride) Structural Formula Illustration

Trospium chloride is a fine, colorless to slightly yellow, crystalline solid. The compound's solubility in water is approximately 1 g/2 mL.

SANCTURA XR® capsules contain 60 mg of trospium chloride to be given orally. Each capsule also contains the following inactive ingredients: sugar spheres, methacrylic acid copolymer, ethyl cellulose, hydroxypropyl methylcellulose, triethyl citrate, talc, and Opadry® white.

What are the possible side effects of trospium (Sanctura, Sanctura XR)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using trospium and call your doctor at once if you urinate less than usual or not at all.

Less serious side effects may include:

dry mouth or throat;
dry eyes, blurred vision;
constipation;
stomach pain, bloating, gas;
drowsiness, or
mild skin rash.

This is not a...

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What are the precautions when taking trospium chloride extended release capsule (Sanctura XR)?

Before taking trospium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain type of glaucoma (uncontrolled narrow-angle type), inability to urinate (urinary retention), delayed or slow emptying of your stomach.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, constipation, other stomach conditions (such as ulcerative colitis, intestinal atony), myasthenia...

Read All Potential Precautions of Sanctura XR »

Last reviewed on RxList: 9/23/2011
This monograph has been modified to include the generic and brand name in many instances.