Sancuso (Granisetron Transdermal System) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Sancuso

Head and Neck Cancer »

What is cancer?

Cancer is a group of many related diseases that begin in cells, the body's basic unit of life. Normally, cells grow and divide to form new cells in an orderly way. They perform their functions for a while, and then they die. Sometimes, however, cells do not die. Instead, they continue to divide and create new cells that the body does not need. The extra cells form a mass of tissue, called a growth or tumor. There are two types of tumors: benign and malignant. Benign tumors are not cancer. They do not invade nearby tissue or spread to other parts of the body. Malignant tumors are cancer. Their growth invades normal structures near the tumor and spreads to other parts of the body. Metastasis is the spread of cancer beyond one location in the body.

What kinds of cancers are considered cancers of the head and neck?

Most head and neck cancers begin in the cells that line the mucosal surfaces in the head and...

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Sancuso

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Sancuso
(Granisetron Transdermal System)

DRUG DESCRIPTION

Sancuso contains granisetron, which is an anti-nauseant and antiemetic agent. Chemically it is 1methyl-N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide with a molecular weight of 312.4. Its empirical formula is C₁₈H₂₄N₄O, while its chemical structure is:

Granisetron

Granisetron is a white to off-white solid that is insoluble in water. Sancuso is a thin, translucent, matrix-type transdermal patch that is rectangular-shaped with rounded corners, consisting of a backing, the drug matrix and a release liner.

What are the possible side effects of transdermal granisetron (Sancuso)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Remove the skin patch and call your doctor at once if you have a serious side effect such as:

severe redness, itching, swelling, or other irritation where the patch is worn;
uneven heart rate;
fever, pale skin, easy bruising or bleeding; or
feeling like you might pass out.

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Sancuso »

What are the precautions when taking granisetron transdermal system (Sancuso)?

Before using granisetron, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal problems (such as ileus, swelling).

This medication may be affected by sunlight or may make the application site more sensitive to sunlight. While wearing the patch, keep it covered (such as under clothing) to avoid exposing it to sunlight and sunlamps. Avoid tanning booths. After removing the patch, keep the application site covered for another 10 days.

During pregnancy, this medication...

Read All Potential Precautions of Sancuso »

Last reviewed on RxList: 10/10/2011
This monograph has been modified to include the generic and brand name in many instances.