Sansert (Methysergide maleate) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

Sansert

Migraine »

What is a migraine headache?

A migraine headache is a form of vascular headache. Migraine headache is caused by vasodilatation (enlargement of blood vessels) that causes the release of chemicals from nerve fibers that coil around the large arteries of the brain. Enlargement of these blood vessels stretches the nerves that coil around them and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the arteries magnifies the pain.

Migraine attacks commonly activate the sympathetic nervous system in the body. The sympathetic nervous system is often thought of as the part of the nervous system that controls primitive responses to stress and pain, the so-called "fight or flight" response, and this activation causes many of the symptoms associated with migraine attacks; for example, the increased sympathetic n...

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Sansert

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Sansert Patient Information including If I Miss a Dose

What happens if I miss a dose (Sansert)?

Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What happens if I overdose (Sansert)?

Seek emergency medical attention.

Symptoms of a methysergide overdose include dizziness, hyperactivity, large pupils, a fast heart rate, euphoria, and, possibly, cold and blue hands and feet.

What should I avoid while taking methysergide (Sansert)?

Use caution when driving, operating machinery, or performing other hazardous activities. Methysergide may cause drowsiness. If you experience drowsiness, avoid these activities.

Weight gain has occurred with methysergide therapy. Maintain a healthy diet and exercise program to prevent weight gain.

What other drugs will affect methysergide (Sansert)?

Certain drugs can lead to poor blood flow if taken with methysergide. This can be dangerous and can cause symptoms such as a cold feeling in your fingers, toes, hands, feet, arms, legs, or nose. In rare but severe cases, gangrene can result. The following drugs should not be taken with methysergide or should be used only under the supervision of your doctor:

other migraine headache medicines such as sumatriptan (Imitrex), zolmitriptan (Zomig), rizatriptan (Maxalt), naratriptan (Amerge), ergotamine (Ergomar), dihydroergotamine (D.H.E.), and others;
beta-blockers (which are used to treat high blood pressure, irregular heartbeats, and other heart conditions) such as carteolol (Cartrol), carvedilol (Coreg), labetalol (Normodyne, Trandate), nadolol (Corgard), pindolol (Visken), propranolol (Inderal), sotalol (Betapace), and timolol (Blocadren); and
nicotine (in cigarettes, smokeless tobacco, and smoking cessation products).

Drugs other than those listed here may also interact with methysergide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has more information about methysergide written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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