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Peptic ulcer facts*

*Peptic ulcer disease facts medically edited by: Jay W. Marks, MD

• Peptic ulcers are sores in the lining of the stomach or duodenum.
• Peptic ulcer formation is related to H. pylori bacteria in the stomach and nonsteroidal anti-inflammatory medications (NSAIDs) in 50% of patients. For the remaining 50% there are miscellaneous or unknown causes.
• Ulcer pain may not correlate with the presence or severity of ulceration.
• The main symptom of peptic ulcer is upper abdominal pain which can be dull, sharp, or burning. (Bloating and burping are not symptoms of peptic ulcer, and vomiting, poor appetite, and nausea are uncommon symptoms of peptic ulcer.)
• Diagnosis of ulcer is made with upper GI series or endoscopy.
• Treatment of ulcers involves antibiotic combinations along with stomach acid suppression to eradicate H. pylori, eliminatin...

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