"Aug. 5, 2013 -- Anyone who develops a rash, blister, or some other skin reaction while taking acetaminophen should stop using the drug and seek medical care immediately. The painkiller poses the risk for three rare but potentially fatal skin diso"...
Santyl Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Santyl (collagenase) is used to help the healing of burns, skin wounds, and skin ulcers. Collagenase is an enzyme. This product is available in generic form. Common side effects include pain or a burning feeling at the affected area. Temporary redness/irritation may also occur in the skin around the affected area.
Santyl is an ointment that is applied once/day to affected areas. Cleanse the areas first with saline solution, and apply any additional antibiotic ointments as directed by your doctor before applying Santyl. Skin products containing heavy metals such as lead, mercury or silver, may decrease the effect of Santyl. There are no warnings about use of this medication during pregnancy. Tell your doctor if you are pregnant. It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding.
Our Santyl Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Santyl in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if your skin condition gets worse, or you have new symptoms of illness or infection.
Less serious side effects may include redness of the skin around the treated area where collagenase topical was applied.
Read the entire detailed patient monograph for Santyl (Collagenase) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Santyl Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Treatment of burns and skin ulcers by breaking up and removing dead skin and tissue may infrequently increase the risk for serious infection (sepsis). Tell your doctor immediately if you notice any symptoms of serious infection, including: fever/chills, fast breathing (hyperventilation), fast heartbeat, warm skin, weakness.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Santyl (Collagenase)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Santyl FDA Prescribing Information: Side Effects
No allergic sensitivity or toxic reactions have been noted in clinical use when used as directed. However, one case of systemic manifestations of hypersensitivity to collagenase in a patient treated for more than one year with a combination of collagenase and cortisone has been reported.
Read the entire FDA prescribing information for Santyl (Collagenase) »
Additional Santyl Information
Santyl - User Reviews
Santyl User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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