font size


SAPHO Syndrome

Medical Author:
Medical Editor:

SAPHO syndrome facts

  • SAPHO syndrome is a chronic disorder that involves the skin, bone, and joints.
  • SAPHO is an acronym for the combination of synovitis, acne, pustulosis, hyperostosis, and osteitis.
  • Some researchers feel that the SAPHO syndrome is related to the group of arthritis conditions which typically affect the spine, called the spondyloarthropathies.
  • Treatment of SAPHO syndrome typically involves medications which reduce inflammation.

What is SAPHO syndrome?

SAPHO syndrome is a chronic disorder that involves the skin, bone, and joints. SAPHO is an acronym for the combination of synovitis, acne, pustulosis, hyperostosis, and osteitis.

Synovitis means inflammation of the joint lining (synovium). Typically, this is manifests as warmth, tenderness, pain, swelling, and stiffness of involved joints (arthritis).

Acne is a skin condition featuring tiny areas of inflammation with pus formation at the hair follicles. Acne occurs most commonly on the face and upper back.

Pustulosis is a very inflammatory skin condition resulting in large fluid-filled blister-like areas (pustules), typically on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes (exfoliates).

Hyperostosis means abnormal excessive growth of bone. The hyperostosis of the SAPHO syndrome frequently is located at the points of the bone where tendons attach, generally in the chest wall.

Osteitis means inflammation of the bone. Patients with SAPHO syndrome can develop inflammation of the sacroiliac joints (sacroiliitis) as well as inflammation of the spine (spondylitis) which leads to stiffness and pain of the neck and back.

Medically Reviewed by a Doctor on 4/30/2014

Patient Comments

Viewers share their comments

SAPHO Syndrome - Symptoms and Diagnosis Question: What symptoms did you experience with SAPHO syndrome? How was it diagnosed?
SAPHO Syndrome - Treatment Question: What types of treatment, including medication, did you receive for your SAPHO syndrome?
Source: MedicineNet.com
http://www.medicinenet.com/sapho_syndrome/article.htm

Arthritis

Get the latest treatment options

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations

NIH talks about Ebola on WebMD