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HIV and AIDS: Treatments and Medications (cont.)

Protease Inhibitors (PIs)

PIs block the action of an HIV enzyme called protease that allows HIV to produce infectious copies of itself within HIV-infected human cells. Thus, blocking protease prevents HIV in already-infected cells from producing HIV that can infect other, not yet infected cells.

Brand Name Generic Names Manufacturer
Agenerase (discontinued) amprenavir, APV GlaxoSmithKline
Aptivus tipranavir, TPV Boehringer Ingelheim
Crixivan indinavir, IDV Merck
Invirase saquinavir mesylate, SQV Hoffmann-La Roche
Kaletra lopinavir and ritonavir, LPV/RTV Abbott Laboratories
Lexiva Fosamprenavir Calcium, FOS-APV GlaxoSmithKline
Norvir ritonavir, RTV Abbott Laboratories
Prezista darunavir Tibotec, Inc.
Reyataz atazanavir sulfate, ATV Bristol-Myers Squibb
Viracept nelfinavir mesylate, NFV Agouron Pharmaceuticals

SOURCES:

The U.S. Food and Drug Administration


Last Editorial Review: 12/3/2009 10:16:25 AM



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